Recurrent septicemia in secondary immunodeficiency induced by nasal steroid abuse
Sepse recorrente induzida por abuso de corticoide nasal em paciente com imunodeficiência secundária
Bruna Giavina-Bianchi; Adriana Pitchon; André Luiz Oliveira Feodrippe; Pedro Giavina-Bianchi
Abstract
Nasal corticosteroids are recommended as first-line therapy for patients with moderate-to-severe allergic rhinitis. We report a case of a patient with secondary immunodeficiency who presented with recurrent septicemia induced by the inappropriate use of nasal corticosteroids, highlighting the risks associated with the misuse of this medication.
Keywords
Resumo
Os corticosteroides nasais são recomendados como terapia de primeira linha para pacientes com rinite alérgica moderada a grave. Relatamos o caso de um paciente com imunodeficiência secundária que apresentou sepse recorrente induzida pelo uso inadequado de corticosteroides nasais, destacando os riscos associados ao uso incorreto desse medicamento.
Palavras-chave
Referências
1. Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315(8):801-10.
2. Cain DW, Cidlowski JA. Immune regulation by glucocorticoids. Nat Rev Immunol. 2017;17(4):233-47.
3. Gurnell M, Heaney LG, Price D, Menzies-Gow A. Long-term corticosteroid use, adrenal insufficiency, and the need for steroid-sparing treatment in adult severe asthma. J Intern Med. 2021;290(2):240-56.
4. Giavina-Bianchi P, Aun MV, Takejima P, Kalil J, Agondi RC. United airway disease: current perspectives. J Asthma Allergy. 2016 May 11;9:93-100.
5. Fuchs M, Wetzig H, Kertscher F, Tãschner R, Keller E. Iatrogenic Cushing syndrome and mutatio tarda caused by dexamethasone containing nose drops. HNO. 1999;47(7):647-50.
Submetido em:
11/11/2024
Aceito em:
12/12/2024
Facebook
Google+
Twitter
LinkedIn
Mendeley
StumbleUpon
CiteULike
Reddit
Email